I am happy to share that a new paper from the Mostajo-Radji and Teodorescu labs at UC Santa Cruz has just been published in Stem Cell Reports: Establishing mouse forebrain organoids as models of intrinsic cortical network assembly. This work, led by Sebastian Hernandez and Hunter Schweiger, establishes dorsal and ventral mouse forebrain organoids as a platform to study how cellular composition, in particular the balance between excitatory and inhibitory neurons, shapes the self-organization of cortical networks.

This wonderful collaborative effort strongly reminds me of our findings in the developing mouse brain. It is exciting to see these principles at play in an organoid system.

Congratulations to Sebastian, Hunter, and the whole team on this fantastic work!