Early rebalancing of neuroinflammatory cascades lastingly rescues prefrontal deficits in a 22q11.2ds model
Cognitive deficits, a characteristic feature of neuropsychiatric disorders, reflect perturbed activity in neuronal networks. Increasing …
Anne Günther , Mattia Chini , Sebastian H. Bitzenhofer , Annette Marquardt , Ileana L. Hanganu-Opatz
Last updated on Feb 2, 2026
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Early rebalancing of neuroinflammatory cascades lastingly rescues prefrontal deficits in a 22q11.2ds model
Resolving and Rescuing Developmental Miswiring in a Mouse Model of Cognitive Impairment
Cognitive deficits, core features of mental illness, largely result from dysfunction of prefrontal networks. This dysfunction emerges …
Mattia Chini , Jastyn A. Pöpplau , Christoph Lindemann , Laura Carol-Perdiguer , Marilena Hnida , Victoria Oberländer , Xiaxia Xu , Joachim Ahlbeck , Sebastian H. Bitzenhofer , Christoph Mulert , Ileana L. Hanganu-Opatz
Last updated on Aug 14, 2025
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Resolving and Rescuing Developmental Miswiring in a Mouse Model of Cognitive Impairment
Sleep Loss Promotes Astrocytic Phagocytosis and Microglial Activation in Mouse Cerebral Cortex
We previously found that Mertk and its ligand Gas6, astrocytic genes involved in phagocytosis, are upregulated after acute sleep …
Michele Bellesi , Luisa De Vivo , Mattia Chini , Francesca Gilli , Giulio Tononi , Chiara Cirelli
Last updated on Aug 14, 2025
PDF DOI
Sleep Loss Promotes Astrocytic Phagocytosis and Microglial Activation in Mouse Cerebral Cortex