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Anesthetics fragment hippocampal network activity, alter spine dynamics, and affect memory consolidation
General anesthesia is characterized by reversible loss of consciousness accompanied by transient amnesia. Yet, long-term memory …
Wei Yang
,
Mattia Chini
,
Jastyn A. Pöpplau
,
Andrey Formozov
,
Alexander Dieter
,
Patrick Piechocinski
,
Cynthia Rais
,
Fabio Morellini
,
Olaf Sporns
,
Ileana L. Hanganu-Opatz
,
J. Simon Wiegert
Last updated on Aug 14, 2025
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DOI
Sleep Loss Promotes Astrocytic Phagocytosis and Microglial Activation in Mouse Cerebral Cortex
We previously found that Mertk and its ligand Gas6, astrocytic genes involved in phagocytosis, are upregulated after acute sleep …
Michele Bellesi
,
Luisa De Vivo
,
Mattia Chini
,
Francesca Gilli
,
Giulio Tononi
,
Chiara Cirelli
Last updated on Aug 14, 2025
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DOI
Contribution of sleep to the repair of neuronal DNA double-strand breaks: evidence from flies and mice
Exploration of a novel environment leads to neuronal DNA double-strand breaks (DSBs). These DSBs are generated by type 2 topoisomerase …
Michele Bellesi
,
Daniel Bushey
,
Mattia Chini
,
Giulio Tononi
,
Chiara Cirelli
Last updated on Aug 14, 2025
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DOI